Receptors, cells & mechanisms responsible for antibody-induced tumor therapy / Récepteurs, cellules et mécanismes impliqués dans la thérapie anti-tumorale à base d'anticorps monoclonaux
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APA-like:
Tác giả chưa xác định. Receptors, cells & mechanisms responsible for antibody-induced tumor therapy / Récepteurs, cellules et mécanismes impliqués dans la thérapie anti-tumorale à base d'anticorps monoclonaux. Thesis, HAL - Pháp.
Việt Nam (chuẩn TCVN 5453:1991):
. Receptors, cells & mechanisms responsible for antibody-induced tumor therapy / Récepteurs, cellules et mécanismes impliqués dans la thérapie anti-tumorale à base d'anticorps monoclonaux. Thesis. HAL - Pháp. Truy cập từ .
Tóm tắt
Monoclonal antibodies (mAbs) can be used to specifically target tumor cells over-expressing specific antigens. In most of the cases, the binding of the mAbs on the target antigen enables via the Fc portion of mAbs the recruitment of phagocytic and/or cytotoxic immune cells bearing receptors for the Fc portion of IgG (FcγR). Several FcγRs exist that differ from each other for both their functional activity and expression pattern among immune cells. Moreover, numerous differences exist between mou...