Human trophoblast lineage characterisation with stem cell models : a dive into human placental development / Etude du trophoblaste humain au moyen de modèles de cellules souches
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Tác giả chưa xác định. Human trophoblast lineage characterisation with stem cell models : a dive into human placental development / Etude du trophoblaste humain au moyen de modèles de cellules souches. Thesis, HAL - Pháp.
Việt Nam (chuẩn TCVN 5453:1991):
. Human trophoblast lineage characterisation with stem cell models : a dive into human placental development / Etude du trophoblaste humain au moyen de modèles de cellules souches. Thesis. HAL - Pháp. Truy cập từ .
Tóm tắt
This thesis focuses on cell lineage specification events occurring in the human embryo and related molecular mechanisms involved in the formation of the placenta. An issue surrounding this field of research is the limited access to human embryos and trophoblast stem cells from patients, notably those related to placental diseases. Therefore, we applied somatic cell reprogramming and cell fate conversion approaches to generate human induced trophoblast stem cells (hiTSCs) from patients’ fibroblas...