Mechanistic dissection of SPEN function during X chromosome inactivation / Fonctions et mécanismes de SPEN pendant l’inactivation du chromosome X
👁 4 lượt xem↓ 0 lượt tải qua VietLexVietLex bảo vệ quyền riêng tư của bạn — không tracking, không chia sẻ thông tin tải về cho bên thứ ba.
📑 Trích dẫn đầy đủ (citation)
APA-like:
Tác giả chưa xác định. Mechanistic dissection of SPEN function during X chromosome inactivation / Fonctions et mécanismes de SPEN pendant l’inactivation du chromosome X. Thesis, HAL - Pháp.
Việt Nam (chuẩn TCVN 5453:1991):
. Mechanistic dissection of SPEN function during X chromosome inactivation / Fonctions et mécanismes de SPEN pendant l’inactivation du chromosome X. Thesis. HAL - Pháp. Truy cập từ .
Tóm tắt
In female placental mammals, dosage compensation of X-linked gene expression is achieved early during development through transcriptional inactivation of one of the two X chromosomes (XCI). This process is dependent on Xist, a long non-coding RNA which coats and silences the X chromosome from which it is transcribed. The mechanisms through which Xist initiates transcriptional silencing during XCI remain however completely unknown. In 2015, several studies identified that the SPEN protein binds X...