Molecular characterization and functional analysis of poor-prognosis B-cell leukemias / Caractérisation moléculaire et analyse fonctionnelle des leucémies B de mauvais pronostic
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APA-like:
Tác giả chưa xác định. Molecular characterization and functional analysis of poor-prognosis B-cell leukemias / Caractérisation moléculaire et analyse fonctionnelle des leucémies B de mauvais pronostic. Thesis, HAL - Pháp.
Việt Nam (chuẩn TCVN 5453:1991):
. Molecular characterization and functional analysis of poor-prognosis B-cell leukemias / Caractérisation moléculaire et analyse fonctionnelle des leucémies B de mauvais pronostic. Thesis. HAL - Pháp. Truy cập từ .
Tóm tắt
The overall aim of this thesis consisted of expanding the current understanding of the genetic basis and physiopathology of aggressive B-cell leukemias, namely in chronic lymphocytic leukemia (CLL) subtypes and in B-cell prolymphocytic leukemia (B-PLL). CLL, the most common form of adult leukemia in the West, is characterized by an accumulation of monoclonal B cells (CD20+, CD5+ and CD23+) in the peripheral blood, bone marrow, and secondary lymphoid organs. CLL is a highly heterogeneous disease,...